Laboratory for Biomolecular Discovery & Engineering
We are particularly interested in discovering new bioactive natural products from human-associated bacteria, elucidating unusual pathways for natural product biosynthesis, unravelling the ecological role and mode of action of natural products, and engineering microbes for the production of novel natural product derivatives and other therapeutic applications.
Research areas
Computational biology Microbiology Medical biotechnologyResearch focus
Our research spans the exciting interface between chemistry & biology and centers around microbial natural products with potential pharmaceutical applications, such as antibiotics, antifungals, immunosuppressants, anticancer agents and other bioactive metabolites. We are particularly interested in discovering new bioactive natural products from human-associated bacteria, elucidating unusual pathways for natural product biosynthesis, unravelling the ecological role and mode of action of natural products, and engineering microbes for the production of novel natural product derivatives and other therapeutic applications.
To accomplish this, we utilise a multidisciplinary research approach, combining microbiology, molecular genetics, genomics, enzymology, bioinformatics, structural biology, analytical chemistry and chemical synthesis.
Publications
To showcase the world-class scientific research of the Joleen Masschelein Lab, you can discover their scientific papers in more detail.
Jobs
We are always on the lookout for highly motivated colleagues to join our team. If you are interested, please contact us.
Team
The Joleen Masschelein Lab can only thrive thanks to the dedication and commitment of its people, no matter what their function or seniority.
Events
To stay up to date in rapidly evolving fields, scientists regularly interact with (international) colleagues. Conferences and other (scientific) events are an excellent way to facilitate such a continent-spanning knowledge exchange.